{"title":"Longevity Research","description":"\u003cp data-pm-slice=\"1 1 []\"\u003e\u003cspan\u003eExplore the evolving science of cellular ageing with the Helix Bio-Science Longevity Research Collection.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis collection features compounds investigated for their roles in mitochondrial function, cellular energy metabolism, oxidative stress responses and the biological processes associated with ageing.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eMitochondrial function and cellular maintenance are important areas of modern longevity research, with scientists investigating how changes in metabolism, energy production and cellular signalling relate to age-associated biological changes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eFrom essential cellular coenzymes to mitochondrial-targeting peptides, this collection brings together compounds relevant to the study of energy regulation and mitochondrial biology.\u003c\/span\u003e\u003c\/p\u003e","products":[{"product_id":"nad","title":"NAD+","description":"\u003ch1\u003e\u003cspan\u003eNAD+ – 1000 mg\u003c\/span\u003e\u003c\/h1\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAdvanced Cellular Coenzyme | Energy, Metabolic \u0026amp; Longevity Research\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eNAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme found in virtually every living cell. It plays an essential role in cellular energy metabolism, mitochondrial function, DNA repair and numerous biological processes associated with cellular maintenance.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eUnlike traditional peptides, NAD+ is a coenzyme that participates directly in hundreds of enzymatic reactions throughout the body.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eScientific interest in NAD+ has increased significantly due to its involvement in ageing-related cellular changes, metabolic regulation and the maintenance of healthy cellular function.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eResearch has demonstrated that NAD+ levels can decline with age in certain tissues, making NAD+ metabolism an important area of investigation in longevity science and molecular biology.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eHow Does NAD+ Work?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eNAD+ participates in several important biological pathways:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCellular Energy Production:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Functions as an essential coenzyme in metabolic reactions that support the production of ATP, the primary energy currency of cells.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMitochondrial Function:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Plays a central role in cellular respiration and the biochemical processes responsible for energy metabolism.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eDNA Repair Mechanisms:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Acts as a substrate for PARP enzymes, which participate in cellular responses to DNA damage and genome maintenance.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eSirtuin Activity:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Supports NAD+-dependent enzymes known as sirtuins, which are involved in metabolic regulation, cellular stress responses and gene expression.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCellular Ageing Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Investigated for its relationship with age-associated changes in cellular metabolism and biological function.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eOxidative Stress Regulation:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Participates in redox reactions that are fundamental to cellular metabolism and oxidative balance.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMetabolic Signalling:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Involved in pathways associated with nutrient sensing, glucose metabolism and cellular energy regulation.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eKey Research Areas\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eCellular energy and ATP metabolism\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eMitochondrial function and cellular respiration\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eDNA repair and genome stability\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eSirtuin activity and cellular signalling\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eAge-associated metabolic changes\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eOxidative stress and redox biology\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eMetabolic and endocrine regulation\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eCellular maintenance and longevity science\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eProduct Information\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e NAD+ (Nicotinamide Adenine Dinucleotide)\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eStrength:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e 1000 mg\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eClassification:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Cellular Coenzyme\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eResearch Category:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Cellular Energy, Metabolic \u0026amp; Longevity Research\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eBrand:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Helix Bio-Science\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eCurrent Scientific Research\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eNAD+ is one of the most extensively studied coenzymes in cellular biology due to its fundamental involvement in energy production and metabolic regulation.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePreclinical studies have investigated NAD+ metabolism in relation to mitochondrial function, cellular ageing, DNA repair and metabolic health.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eHuman studies involving NAD+ precursors, including nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), have demonstrated increases in certain NAD-related biomarkers. However, improvements in physical performance, cognitive function, energy levels and biological ageing have not been consistently established.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eClinical evidence specifically supporting injectable or intravenous NAD+ for anti-ageing and wellness remains limited.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eFurther controlled human trials are required to determine whether increasing NAD+ availability produces meaningful, sustained health benefits.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eImportant Research Disclaimer\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eNAD+ is a naturally occurring biological coenzyme. However, experimental NAD+ formulations intended for administration have not been established as safe or effective treatments for anti-ageing, fatigue, cognitive enhancement or metabolic disorders.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eInjectable NAD+ formulations may carry risks associated with contamination, adverse reactions and uncertain long-term safety.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFor research use only. Not for human or animal consumption. Not intended to diagnose, treat, cure or prevent any disease.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"Helix Bio-Science","offers":[{"title":"Default Title","offer_id":60150550430041,"sku":null,"price":100.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1094\/3850\/1209\/files\/35266DB6-0006-4238-8676-89F172BBB05E.png?v=1792910118"},{"product_id":"ss-31","title":"SS-31","description":"\u003ch1\u003e\u003cspan\u003eSS-31 (Elamipretide) – 10 mg\u003c\/span\u003e\u003c\/h1\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAdvanced Mitochondrial-Targeting Peptide | Cellular Energy \u0026amp; Mitochondrial Research\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eSS-31, scientifically known as \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eElamipretide\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, is a synthetic tetrapeptide specifically designed to interact with the inner mitochondrial membrane.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAlso referred to as MTP-131, SS-31 has attracted significant scientific interest for its interaction with cardiolipin, a specialised phospholipid essential for maintaining mitochondrial structure and function.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eMitochondria play a central role in cellular energy production, making mitochondrial function an important area of investigation in metabolic health, cellular ageing and disease research.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eSS-31 has become a major focus of scientific studies investigating mitochondrial membrane stability, cellular respiration and energy metabolism.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eHow Does SS-31 Work?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eSS-31 interacts with the mitochondrial inner membrane and influences several important biological mechanisms:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMitochondrial Membrane Interaction:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Binds to cardiolipin, a phospholipid involved in maintaining the structure and organisation of mitochondrial membranes.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCellular Energy Production:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Investigated for its effects on mitochondrial respiration and ATP-generating processes.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eOxidative Stress Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Studied for its influence on mitochondrial reactive oxygen species and cellular oxidative balance.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMitochondrial Structural Integrity:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Research has examined its potential to preserve the organisation of mitochondrial cristae and associated proteins.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eCellular Stress Responses:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Investigated for its effects on mitochondrial dysfunction associated with metabolic or oxidative stress.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eMuscle \u0026amp; Cardiac Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Studied in experimental and clinical settings involving mitochondrial function in skeletal and cardiac muscle.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eAge-Associated Mitochondrial Changes:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Investigated for its effects on mitochondrial energy regulation in ageing-related experimental models.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eKey Research Areas\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eMitochondrial membrane integrity\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eCardiolipin interactions and membrane organisation\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eCellular respiration and ATP production\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eOxidative stress and mitochondrial signalling\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eAge-associated mitochondrial dysfunction\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eSkeletal muscle and cardiac energy metabolism\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eMitochondrial structure and cellular maintenance\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003e\u003cspan\u003eMitochondrial disease research\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cspan\u003eProduct Information\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eProduct:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e SS-31 (Elamipretide)\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eStrength:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e 10 mg\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eClassification:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Synthetic Mitochondrial-Targeting Tetrapeptide\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003ePeptide Length:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e 4 Amino Acids\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Formula:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e C₃₂H₄₉N₉O₅\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eMolecular Weight:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Approximately 639.8 Da\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eCAS Number:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e 736992-21-5\u003c\/span\u003e\u003cbr\u003e\u003cstrong\u003e\u003cspan\u003eBrand:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e Helix Bio-Science\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eCurrent Scientific Research\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eSS-31 has been extensively investigated in preclinical studies focusing on mitochondrial structure, energy production and cellular responses to stress.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eResearch has demonstrated interactions between Elamipretide and cardiolipin within the mitochondrial inner membrane.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAdditional experimental studies have explored its effects on mitochondrial ATP production, oxidative stress and skeletal muscle function.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIn September 2025, the US Food and Drug Administration granted accelerated approval to the prescription medicine Forzinity (Elamipretide) to improve muscle strength in adults and children with Barth syndrome weighing at least 30 kg.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThis approval relates to a specific pharmaceutical formulation and clinical indication. It does not establish benefits for general anti-ageing, athletic performance or wellness purposes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eFurther research continues to investigate its activity across other conditions associated with mitochondrial dysfunction.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eImportant Research Disclaimer\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eSS-31 is the research designation associated with Elamipretide, an active pharmaceutical compound with a specific approved prescription indication in the United States.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eResearch-grade SS-31 is not equivalent to an approved medicinal formulation and must not be represented as a substitute for prescription Elamipretide.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eIts safety and effectiveness for general longevity, athletic performance, energy enhancement or other unapproved applications have not been established.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFor research use only. Not for human or animal consumption. Not intended to diagnose, treat, cure or prevent any disease.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"Helix Bio-Science","offers":[{"title":"Default Title","offer_id":60150579790169,"sku":null,"price":25.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1094\/3850\/1209\/files\/9DD46C00-96D6-4262-90A2-E6AECAB83C45.png?v=1792910467"}],"url":"https:\/\/helix-bioscience.com\/collections\/longevity-research.oembed","provider":"Helix Bio-Science","version":"1.0","type":"link"}