SS-31 (Elamipretide) – 10 mg

Advanced Mitochondrial-Targeting Peptide | Cellular Energy & Mitochondrial Research

SS-31, scientifically known as Elamipretide, is a synthetic tetrapeptide specifically designed to interact with the inner mitochondrial membrane.

Also referred to as MTP-131, SS-31 has attracted significant scientific interest for its interaction with cardiolipin, a specialised phospholipid essential for maintaining mitochondrial structure and function.

Mitochondria play a central role in cellular energy production, making mitochondrial function an important area of investigation in metabolic health, cellular ageing and disease research.

SS-31 has become a major focus of scientific studies investigating mitochondrial membrane stability, cellular respiration and energy metabolism.

How Does SS-31 Work?

SS-31 interacts with the mitochondrial inner membrane and influences several important biological mechanisms:

• Mitochondrial Membrane Interaction: Binds to cardiolipin, a phospholipid involved in maintaining the structure and organisation of mitochondrial membranes.

• Cellular Energy Production: Investigated for its effects on mitochondrial respiration and ATP-generating processes.

• Oxidative Stress Research: Studied for its influence on mitochondrial reactive oxygen species and cellular oxidative balance.

• Mitochondrial Structural Integrity: Research has examined its potential to preserve the organisation of mitochondrial cristae and associated proteins.

• Cellular Stress Responses: Investigated for its effects on mitochondrial dysfunction associated with metabolic or oxidative stress.

• Muscle & Cardiac Research: Studied in experimental and clinical settings involving mitochondrial function in skeletal and cardiac muscle.

• Age-Associated Mitochondrial Changes: Investigated for its effects on mitochondrial energy regulation in ageing-related experimental models.

Key Research Areas

• Mitochondrial membrane integrity

• Cardiolipin interactions and membrane organisation

• Cellular respiration and ATP production

• Oxidative stress and mitochondrial signalling

• Age-associated mitochondrial dysfunction

• Skeletal muscle and cardiac energy metabolism

• Mitochondrial structure and cellular maintenance

• Mitochondrial disease research

Product Information

Product: SS-31 (Elamipretide)
Strength: 10 mg
Classification: Synthetic Mitochondrial-Targeting Tetrapeptide
Peptide Length: 4 Amino Acids
Molecular Formula: C₃₂H₄₉N₉O₅
Molecular Weight: Approximately 639.8 Da
CAS Number: 736992-21-5
Brand: Helix Bio-Science

Current Scientific Research

SS-31 has been extensively investigated in preclinical studies focusing on mitochondrial structure, energy production and cellular responses to stress.

Research has demonstrated interactions between Elamipretide and cardiolipin within the mitochondrial inner membrane.

Additional experimental studies have explored its effects on mitochondrial ATP production, oxidative stress and skeletal muscle function.

In September 2025, the US Food and Drug Administration granted accelerated approval to the prescription medicine Forzinity (Elamipretide) to improve muscle strength in adults and children with Barth syndrome weighing at least 30 kg.

This approval relates to a specific pharmaceutical formulation and clinical indication. It does not establish benefits for general anti-ageing, athletic performance or wellness purposes.

Further research continues to investigate its activity across other conditions associated with mitochondrial dysfunction.

Important Research Disclaimer

SS-31 is the research designation associated with Elamipretide, an active pharmaceutical compound with a specific approved prescription indication in the United States.

Research-grade SS-31 is not equivalent to an approved medicinal formulation and must not be represented as a substitute for prescription Elamipretide.

Its safety and effectiveness for general longevity, athletic performance, energy enhancement or other unapproved applications have not been established.

For research use only. Not for human or animal consumption. Not intended to diagnose, treat, cure or prevent any disease.